Does Metformin cause weight loss for you? I have been on Metformin twice daily for 2 years now. I did notice slight weight loss from the time I started the medication. But over the past 6 month period I have lost 14lbs. I did some research and find that Metformin causes some noticeable weight loss in lot of people. Have a look at this: Source The last tail in the graph is the one that represents data of people who have been adherent on metformin . Seems like the correleation is clear. The only thing is this graph indicates 5% weight loss to be common - but I underwent around 8% weight loss - this without much exercise and a hearty diet. What's your experience with Metformin?